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August 26, 2009
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Endocyte Announces Achievement of Second Milestone in Collaboration With
Bristol-Myers Squibb
Endocyte, Inc., a cancer drug discovery and
development company, today announced it has received a milestone payment from Bristol-Myers
Squibb Company (NYSE: BMY). This payment was triggered by the commencement of a Phase
II clinical trial for an epothilone-folate anti-cancer agent identified through the collaboration
between Endocyte and Bristol-Myers Squibb scientists.
“We are pleased to see the advancement of the epothilone-folate compound by our outstanding
partner Bristol-Myers Squibb.” said Ron Ellis, president and CEO of Endocyte. “This further
validates Endocyte’s targeting platform and its leadership position in this space.”
Bristol-Myers Squibb and Endocyte entered into an exclusive license agreement with respect to
the compound in 2005. Bristol-Myers Squibb is responsible for all development, manufacturing,
registration and marketing of the epothilone-folate chemotherapeutic agent.
About Endocyte
Endocyte is a privately-held biotechnology company with headquarters in the Purdue Research
Park of West Lafayette, IN. Based on the applications of Endocyte’s advanced proprietary Drug
Guidance System (DGS), the Company is working to develop new drugs and diagnostic agents
to treat many types of cancer and other serious diseases. The DGS platform makes it possible to
use highly-potent drugs on extended and frequent dosing schedules and in combination with
other drugs to maximize efficacy. The technology improves drug targeting and reduces the risk
of side effects by combining drugs with ligands that target and bind with high affinity to
receptors found on tumor and other disease cells. Endocyte is currently conducting three separate
Phase 2 clinical trials for its lead compound, EC145, together with EC20, a companion
molecular imaging agent, for the treatment of ovarian cancer and non-small cell lung cancer.
Other clinical-stage products in the Endocyte pipeline include: EC0225, a combination of two
potent anticancer drugs; EC17, a targeted immunotherapy agent; and EC0489, a targeted cancer
drug. The Company also has multiple product candidates in pre-clinical stage development.
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